AB1241 FACTORS ASSOCIATED TO LOSS FOR FOLLOW-UP IN A PROSPECTIVE GOUT COHORT

Background Adherence to treatment has been widely studied, but not adherence follow-up visits. Objectives To analyze factors associated loss for in patients with gout and a programmed visit the rheumatology office. Methods Analysis of data from an inception cohort prospectively followed-up university hospital setting. Variables include general data, along clinical characteristics gout, comorbidities, prescribed urate-lowering therapy (ULT). Those variables (p<0.20) bivariate analysis were included multivariate analysis. Patients who did attend because they passed considered as lost follow-up. Results From series 1,442 consecutive patients, 354 (24.5%) follow-up; 219 (15.2%) attended died between Mean until was 32 months vs. 49 still remained active Age (older), gender (women), pooled comorbidity (higher), severity (monoarticular), alcohol intake (<15 g/day), (MPR> 80%), previous (none), consultation (primary care), higher rates No association found persistence on time onset presence tophi, number flares per year, ULT. B Sig. Exp(B) 95% C.I.L. EXP(B) Lower Upper (year ) -,029 ,001 ,972 ,955 ,989 Primary care -1,651 ,008 ,192 ,057 ,647 (MPR > 0.8 -1,120 ,000 ,326 ,186 ,572 Severity (polyarticular -,358 ,107 ,699 ,416 ,1,17 Highest (Kaiser 3-4) ,199 ,519 1,220 ,666 2,234 Previous ULT (none) -,196 ,477 1,217 ,709 2,089 Gender (male) ,256 ,566 1,292 ,539 ,988 Ethanol >15g/day ,005 ,987 ,995 ,543 1,823 In (Table 1), only age, prescribed, primary independently disease) seemed be also persistence, lacked statistical significance. Conclusion our setting, profile at risk abandoning is that younger, poorly adherent, lower burden disease consulting through assistance “short-cut”. Acknowledgements Cruces Rheumatology Association. Disclosure Interests Fernando Perez-Ruiz Speakers bureau: Menarini, Astellas, Consultant of: Arthriti, Anylam, Selecta, LG, Protalix, Cristina Vazquez-Puente: None declared, Maria del Consuelo Modesto-Caballero: Ana Herrero-Beites: declared.